METHOD FOR PREDICTING THE PHENOTYPIC EFFECTS OF MOLECULAR AGENTS WITH THERAPEUTIC POTENTIAL

Description

Drugs exert their effect by inhibiting the functions of the products of genes whose alteration causes the disease or symptoms they are intended to treat. A drug's activity can lead to unwanted side effects due to its interaction with other molecular targets besides the one it is intended to inhibit. This can produce pathological phenotypes in patients.

This invention presents a method that allows for the early prediction of the effects a drug or therapeutic compound may have on the body, including both beneficial and adverse effects. To achieve this, the system analyzes large networks of information that link molecules, proteins, genes, diseases, and symptoms.

Based on these connections, the method identifies the effects that might occur when an agent interacts with certain biological targets, thus providing a useful tool for understanding and anticipating the behavior of a drug before conducting complex trials.

Advantages

This method reduces the costs and time involved in developing new drugs by predicting potential side effects in advance, thus narrowing and focusing subsequent experimental and clinical trials. It increases safety by anticipating potential risks and also helps discover new therapeutic applications for existing drugs. Furthermore, it provides valuable information on the biological mechanisms involved, facilitating decision-making in research and development.

Uses and Applications

The technology can be applied to the design and evaluation of new drugs, the identification of adverse effects, drug repurposing, and the study of combination therapies. It is also useful as a support tool for researchers seeking to understand how diseases, genes, and clinical effects are related.